1. Disturbance of consciousness (i.e., reduced clarity of awareness of the environment) with reduced ability to focus, sustain, or shift attention.
2. A change in cognition (such as memory deficit, disorientation, language disturbance) or the development of a perceptual disturbance that is not better accounted for by a preexisting, established, or evolving dementia.
3. The disturbance develops over a short period of time (usually hours to days) and tends to fluctuate during the course of the day.
4. There is evidence from the history, physical examination, or laboratory findings of either (1) or (2):
   1. the symptoms in Criteria A and B developed during substance intoxication
   2. medication use is etiologically related to the disturbance*
      Note: This diagnosis should be made instead of a diagnosis of substance intoxication only when the cognitive symptoms are in excess of those usually associated with the intoxication syndrome and when the symptoms are sufficiently severe to warrant independent clinical attention.
      *Note: The diagnosis should be recorded as substance-induced delirium if related to medication use.

Code (Specific substance) intoxication delirium:
(Alcohol; Amphetamine [or amphetaminelike substance]; Cannabis; Cocaine; Hallucinogen; Inhalant; Opioid; Phencyclidine [or phencyclidinelike substance]; Sedative, hypnotic, or anxiolytic; Other [or unknown] substance [e.g., cimetidine, digitalis, benztropine])