Selective Serotonin Reuptake Inhibitors (SSRIs)

DRUGS

• Citalopram (Celexa)
• Escitalopram (Lexapro)
• Fluoxetine (Prozac)
• Fluvoxamine (Luvox)
• Paroxetine (Paxil)
• Reboxetine (Edronax/Norebox)
• Sertraline (Zoloft)

THERAPEUTIC INDICATIONS

• Depression
  • Suicidal ideation
  • Depression during Pregnancy & Postpartum
  • Depression in the Elderly & Medically Ill
  • Depression in Children
• Anxiety Disorders
  • OCD
  • PD
  • SP
  • PTSD
  • GAD
• Eating Disorders
  • Bulimia Nervosa
  • Anorexia Nervosa
  • Obesity
• Premenstrual Dysphoric Disorder

ADVERSE EFFECTS

• Sexual Dysfunction (50-80%)
• Gastro-intestinal
  • [nausea, diarrhea, anorexia, vomiting, flatulence, dyspepsia]
• Neuropsychiatric
  • [headache (18-20%), insomnia, sedation, emotional blunting, seizures, extrapyramidal symptoms]

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