Valproate

DRUGS

• Devalproex (Depakote)
• Valproic Acid (Depakene)

THERAPEUTIC INDICATIONS

• Bipolar I Disorder
• Acute Mania
• Mixed Episodes
• Acute Bipolar Depression
• Prophylaxis
• Schizophrenia
• Schizoaffective Disorder

ADVERSE EFFECTS

• Hematological
• [thrombocytopenia]
• Gastro-intestinal
• [hepatotoxicity, pancreatitis]
• Neuropsychiatric
• [somnolence]

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