DRUGS

• Alprazolam (Xanax)
• Clonazepam (Klonopin)
• Diazepam (Valium)
• Estazolam (ProSom)
• Eszopiclone (Lunesta)
• Flumazenil (Romazicon)
• Flurazepam (Dalmane)
• Halazepam (Paxipam)
• Indipon (-)
• Lorazepam (Ativan)
• Midazolam (Versed)
• Oxazepam (Serax)
• Prazepam (Centrax)
• Quazepam (Doral)
• Temazepam (Restoril)
• Triazolam (Halcion)
• Zaleplon (Sonata)
• Zolpidem (Ambien)

THERAPEUTIC INDICATIONS

• Insomnia
• Anxiety Disorders
  • GAD
  • PD
  • SP
• Mixed Anxiety-Depressive Disorder
• Bipolar I Disorder
• Akathisia
• Parkinson's Disease

ADVERSE EFFECTS

• Neuropsychiatric
  • [ataxia (<2%), dizziness (<1%), drowsiness]

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DRUGS

• Citalopram (Celexa)
• Escitalopram (Lexapro)
• Fluoxetine (Prozac)
• Fluvoxamine (Luvox)
• Paroxetine (Paxil)
• Reboxetine (Edronax/Norebox)
• Sertraline (Zoloft)

THERAPEUTIC INDICATIONS

• Depression
  • Suicidal ideation
  • Depression during Pregnancy & Postpartum
  • Depression in the Elderly & Medically Ill
  • Depression in Children
• Anxiety Disorders
  • OCD
  • PD
  • SP
  • PTSD
  • GAD
• Eating Disorders
  • Bulimia Nervosa
  • Anorexia Nervosa
  • Obesity
• Premenstrual Dysphoric Disorder

ADVERSE EFFECTS

• Sexual Dysfunction (50-80%)
• Gastro-intestinal
  • [nausea, diarrhea, anorexia, vomiting, flatulence, dyspepsia]
• Neuropsychiatric
  • [headache (18-20%), insomnia, sedation, emotional blunting, seizures, extrapyramidal symptoms]

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DRUGS

• Desvenlafaxine (Pristiq)
• Duloxetine (Cymbalta)
• Milnacipran (-)
• Venlafaxine (Effexor)

THERAPEUTIC INDICATIONS

• Depression
• Anxiety Disorders
• GAD
• SP
• PD

ADVERSE EFFECTS

• Sexual Dysfunction
• [abnormal ejaculation/orgasm, erectile disturbances, impotence]
• Gastro-intestinal
• [nausea, constipation, dry mouth]
• Neuropsychiatric
• [somnolence, dizziness, nervousness]
• Visual System
• [blurred vision]

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DRUGS

• Brofaromine (Consonar)
• Clorgyline (-)
• Isocarboxazid (Marplan)
• Moclobemide (Manerix)
• Phenelzine (Nardil)
• Selegiline (Eldepryl/EmSam)
• Tranylcypromine (Parnate)

THERAPEUTIC INDICATIONS

• Depression

Adverse effects

• Sexual Dysfunction
• Cardiovascular
• [orthostatic hypotension, edema]
• Gastro-intestinal
• [weight gain]
• Neuropsychiatric
• [insomnia, dizziness]

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DRUGS

• Amitriptyline (Elavil/Endep)
• Amoxapine (Asendin)
• Clomipramine (Anafranil)
• Desipramine (Norpramin/Pertofran)
• Doxepine (Adapin/Sinequan)
• Imipramine (Tofranil)
• Maprotiline (Ludiomil)
• Nortriptyline (Pamelor/Aventyl)
• Trimipramine (Surmontil)

THERAPEUTIC INDICATIONS

• MDD
• Anxiety Disorders
• PD+AG
• GAD
• OCD
• Pain

ADVERSE EFFECTS

• Cardiovascular
• [tachycardia, orthostatic hypotension, conduction abnormalities]
• Gastro-intestinal
• [constipation, dry mouth]
• Neuropsychiatric
• [sedation, seizures]

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DRUGS

• Aripiprazole (Abilify)
• Clozapine (Clozaril)
• Olanzapine (Zyprexa)
• Paliperidone (Invega)
• Quetiapine (Seroquel)
• Risperidone (Risperdal)
• Ziprasidone (Geodon)

THERAPEUTIC INDICATIONS

• Schizophrenia
• Schizoaffective Disorder
• Acute Mania
• Resistant Depression
• PTSD
• Behavioral Disturbances associated with Dementia

ADVERSE EFFECTS

• Sexual Dysfunction
• [abnormal ejaculation]
• Cardiovascular
• [orthostatic hypotension]
• Gastro-intestinal
• [weight gain]
• Neuropsychiatric
• [somnolence, tardive dyskinesia, neuroleptic malignant syndrome]

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DRUGS

PHENOTHIAZINES

• Acetophenazine (Tindal)
• Butaperazine (Repoise)
• Carphenazine (Proketazine)
• Chlorpromazine (Thorazine)
• Fluphenazine (Prolixin/Permitil)
• Mesoridazine (Serentil)
• Perphenazine (Trilafon)
• Piperacetazine (Quide)
• Prochlorperazine (Compazine)
• Promazine (Sparine)
• Thioridazine (Mellaril)
• Trifluoperazine (Stelazine)
• Triflupromazine (Vesprin)

BUTYROPHENONES

• Droperidol (Inapsine)
• Haloperidol (Haldol)

THIOXANTHENES

• Chlorprothixene (Taractan)
• Thiothixene (Navane)

OTHER

• Loxapine (Loxitane)
• Molindone (Moban)
• Pimozide (Orap)
• Reserpine (Diupres)
• Sulpiride (Dogmatil/Sesif)

THERAPEUTIC INDICATIONS

• Schizophrenia
• Schizoaffective Disorder
• Acute Mania
• Depression with psychotic symptoms
• Delusional Disorder
• Borderline Personality Disorder
• Dementia
• Delirium
• Substance-induced Psychotic Disorder
• Tourette's Syndrome
• Huntington's Disease
• Pervasive Developmental Disorder

ADVERSE EFFECTS

• Cardiovascular
• [tachycardiadecreased contractility, orthostatic hypotension, sudden death]
• Gastro-intestinal
• [constipation, dry mouth]
• Neuropsychiatric
• [acute dystonia, akathisia, sedation, tardive dyskinesia, neuroleptic malignant syndrome, acute extrapyramidal effects]

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DRUGS

• Clonidine (Catapres)
• Guanfacine (Tenex)

THERAPEUTIC INDICATIONS

• Withdrawal from Opioids, Alcohol, Benzodiazepines, or Nicotine
• Tourette's Disorder
• Tic Disorders
• Hyperactivity and Aggression in Children
• PTSD

ADVERSE EFFECTS

• Sexual Dysfunction
• Cardiovascular
• [hypotension]
• Gastro-intestinal
• [nausea, constipation, dry mouth]
• Neuropsychiatric
• [fatigue, sedation, dizziness]

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DRUGS

• Acebutolol (Sectral)
• Atenolol (Tenormin)
• Labetalol (Normodyne, Trandate)
• Metoprolol (Lopressor, Toprol)
• Nadolol (Corgard)
• Pindolol (Visken)
• Propranolol (Inderal)

THERAPEUTIC INDICATIONS

• Anxiety Disorders
• SP
• PD
• PTSD
• GAD
• Lithium-induced tremor
• Neuroleptic-induced akathisia
• Adjunctive therapy for Alcohol Withdrawal
• Adjunctive therapy for Aggressive/Violent Behaviour

ADVERSE EFFECTS

• Respiratory
• [asthma]
• Sexual Dysfunction
• [impotence]
• Cardiovascular
• [hypotension, bradycardia, dizziness, congestive heart failure]
• Gastro-intestinal
• [nausea, diarrhea, abdominal pain]
• Neuropsychiatric
• [lassitude, fatigue, dysphoria, insomnia, vivid nightmares, depression, psychosis]

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DRUGS

• Cetirizine (Zyrtec)
• Cyproheptadine (Periactin)
• Diphenydramine (Benadryl)
• Fexofenadine (Allegra)
• Hydroxyzine (Atarax, Vistaril)
• Loratadine (Claritin)
• Promethazine (Phenergan)

THERAPEUTIC INDICATIONS

• Neuroleptic-induced
• Parkinsonism
• Acute Dystonia
• Akathisia

ADVERSE EFFECTS

• Cardiovascular
• [hypotension, dizziness]
• Gastro-intestinal
• [epigastric distress, nausea, vomiting, diarrhea, constipation, dry mouth]
• Neuropsychiatric
• [poor motor coordination, sedation]
• Visual System
• [blurred vision]

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DRUGS

• Amlodipine (Lotrel, Norvasc)
• Diltiazem (Cardizem)
• Isradipine (DynaCirc)
• Nifedipine (Adalat, Procardia)
• Nimodipine (Nimotop)
• Verapamil (Calan, Isoptin)

THERAPEUTIC INDICATIONS

• Bipolar Disorder

Adverse effects

• Cardiovascular
• [hypotension, dizziness, tachycardia, peripheral edema]
• Gastro-intestinal
• [nausea, constipation]
• Neuropsychiatric
• [fatigue, (diltiazem : ) hyperactivity, parkinsonism]

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DRUGS

• Apomorphine (Apokyn)
• Bromocriptine (Parlodel)
• Carbidopa (Lodosyn)
• Levodopa (Larodopa)
• Pergolide (Permax)
• Ropinirole (Requip)

THERAPEUTIC INDICATIONS

• Medication-induced Movement Disorders
• Parkinsonism
• Extrapyramidal symptoms
• Akinesia
• Focal perioral tremor
• Mood Disorders
• Adjunctive therapy for Depression
• Adjunctive therapy for Bipolar II Disorder - Depression
• Sexual Dysfunction

ADVERSE EFFECTS

• Cardiovascular
• [orthostatic hypotension, dizziness, cardiac arrhythmias]
• Gastro-intestinal
• [nausea, vomiting]
• Neuropsychiatric
• [headache]

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DRUGS

• Lithium (Eskalith, Lithobid, Lithonate)

THERAPEUTIC INDICATIONS

• Mood Disorders
• Bipolar I Disorder
• Manic Episodes
• Depressive Episode
• Bipolar II Disorder
• Rapid-cycling Bipolar I Disorder
• Cyclothymic Disorder
• MDD
• Acute Depression
• Maintenance therapy
• Schizoaffective Disorder
• Schizophrenia
• Cognitive Disorders
• Mental Retardation

ADVERSE EFFECTS

• Cardiovascular
• [Benign T-wave changes, sinus node dysfunction]
• Endocrine
• [hypothyroidism, exopthalmos, hyperparathyroidism, adenoma]
• Gastro-intestinal
• [appetite loss, nausea, vomiting, diarrhea]
• Dermatologic
• [acne, hair loss, psoriasis, rash]
• Neuropsychiatric
• [dysphoria, lack of spontaneity, slowed reaction time, postural tremor, coarse tremor, dysarthria, ataxia, neuromuscular irritability, seizures, coma, death, peripheral neuropathy, benign intracranial hypertension, myasthenia gravis-like syndrome]

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DRUGS

• Amphetamine (-)
• Atomoxetine (Strattera)
• Benzphetamine (Didrex)
• Dexfenfluramine (-)
• Dextroamphetamine (Dexedrine)
• Diethylopropion (Tenuate)
• Fenfluramine (Pondimin)
• Mazindol (Mazanor, Sanorex)
• Methamphetamine (Desoxyn)
• Methylphenidate (Ritalin)
• Modafinil (Provigil)
• Pemoline (Cylert)
• Phendimetrazine (Adipost, Bontril)
• Phenmetrazine (Prelude)
• Phentermine (Adipex-P, Fastin, Ionamine)

THERAPEUTIC INDICATIONS

• Attention-Deficit/Hyperactivity Disorder
• Narcolepsy and Hypersomnolence
• Depressive Disorders
• Encephalopathy caused by Brain Injury
• Obesity
• Fatigue

ADVERSE EFFECTS

• Cardiovascular
• [dizziness]
• Gastro-intestinal
• [anorexia, nausea, weight loss]
• Neuropsychiatric
• [insomnia, nightmares, irritability, dysphoria, moodiness, agitation]

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DRUGS

• Trazodone (Desyrel)

THERAPEUTIC INDICATIONS

• Depressive Disorders
• Insomnia
• Erectile Disorder
• Severe Agitation in Children with Developmental Disabilities or Elderly Persons with Dementia

ADVERSE EFFECTS

• Cardiovascular
• [orthostatic hypotension, dizziness]
• Gastro-intestinal
• [nausea]
• Neuropsychiatric
• [headache]

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DRUGS

• Devalproex (Depakote)
• Valproic Acid (Depakene)

THERAPEUTIC INDICATIONS

• Bipolar I Disorder
• Acute Mania
• Mixed Episodes
• Acute Bipolar Depression
• Prophylaxis
• Schizophrenia
• Schizoaffective Disorder

ADVERSE EFFECTS

• Hematological
• [thrombocytopenia]
• Gastro-intestinal
• [hepatotoxicity, pancreatitis]
• Neuropsychiatric
• [somnolence]

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DRUGS

• Amantadine (Symmetrel)
• Benztropine (Cogentin)
• Biperiden (Akineton)
• Cycrimine (Pagitane)
• Ethopropazine (Parsidol)
• Orphenadrine (Norflex, Dispal)

THERAPEUTIC INDICATIONS

• Neuroleptic-induced Parkinsonism
• Neuroleptic-induced Acute Dystonia
• Akathisia

ADVERSE EFFECTS

• Cardiovascular
• [tachycardia, (amantadine : ) arrhythmia]
• Gastro-intestinal
• [constipation, dry mouth, nausea]
• Neuropsychiatric
• [confusion, disorientation, memory impairment, (amantadine : ) delirium, dementia, paresthesias]
• Visual System
• [blurred vision, dilated pupils, worsening of narrow-angle glaucoma]
• Urogenital
• [urinary retention]

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By Group

1. Benzodiazepines


2. SSRIs (Selective Serotonin Reuptake Inhibitors)


3. SSNRIs (Selective Serotonin-Norepinephrine Reuptake Inhibitors)


4. MAOIs (Monoamine Oxidase Inhibitors)


5. TCAs (Tricyclic & Tetracyclic Antidepressants)


6. SDAs (Serotonin-Dopamine Antagonists) / Atypical Antipsychotics


7. DRAs (Dopamine Receptor Antagonists) / Typical Antipsychotics


8. α₂-Adrenergic Receptor Agonists


9. β-Adrenergic Receptor Antagonists


10. Antihistamines


11. Calcium Channel Inhibitors


12. Dopamine Receptor Agonists & Precursors


13. Lithium


14. Sympathomimetics & Related Drugs


15. Trazodone


16. Valproate


17. Anticholinergics & Amantadine

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